For resource-constrained fly labs
Every protocol assumes a fully-stocked lab. Yours might not be.
Praxis answers troubleshooting questions against a real corpus of protocols and substitutions that have actually worked in labs like yours — with citations, not guesses.
See it in action ↓Protocols don’t fail. Supply chains do.
Grounded, not guessed
Paste a protocol. Get it annotated.
Every substitution links back to where it came from — a published alternative method, or a swap another researcher logged as working.
RNA extraction — step 3
Homogenize larvae in 1 mL TRIzol Reagent (Invitrogen) on ice.
No local supplier for TRIzol — substitute a phenol-chloroform extraction prepared in-house. See protocol #14 ↗
Ask it directly
Context you can have a conversation with
What can I use instead of TRIzol for RNA extraction?
No local supplier stocks TRIzol. A phenol-chloroform extraction prepared in-house is a direct substitute — logged as successful in 6 of 6 attempts.
Try another question
Why this is safe to trust
It says what it doesn’t know.
Grounded in a real corpus
Every answer is retrieved from actual protocols and logged substitutions — not generated from general knowledge about lab chemistry.
Uncertainty stays visible
When nothing in the corpus covers a question, it says so and points to a senior researcher, instead of improvising a plausible-sounding answer.
Grows from real use
Every substitution a researcher logs as working, or not, feeds back into the corpus for the next person who asks the same question.
What the corpus covers
Standard protocols, indexed
FlyBase, Bloomington documentation, and published methods papers, searchable in plain language.
A substitution log that grows
Every swap a researcher confirms — or rules out — becomes part of the corpus for the next person asking.
Citations, not confidence alone
Answers link back to the protocol or logged attempt they came from, so you can check the source yourself.
Built around one lab's constraints
Started from what's actually available at DRTC, not a generic assumption of a fully-stocked Western lab.
Join the waitlist for early access
We’ll reach out when the pilot is ready to run on a protocol from your own bench.
Prefer email? Reach out directly at hello@metronsolutions.uk